Hydroxypropyl Methylcellulose – Applications and Benefits

Hydroxypropyl Methylcellulose – Applications and Benefits

SidleyCel Hydroxypropyl Methylcellulose

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SidleyCel™ Hydroxypropyl MethylCellulose product is a non-ionic cellulose ether made through a series of chemical processes, with the natural polymer cellulose as the raw material. The product is a non-ionic cellulose ether in the shape of white powder, odorless and tasteless. In cold water, it swells into a clear or slightly turbid colloidal solution. It has thickening, adhesion, dispersion, emulsification, film-formation, suspension, gelation, surface activity, water retention, providing protective colloids and other properties. Hydroxypropyl methylcellulose (HPMC) can be used in building materials, synthetic resin, ceramic industry, medicine, food, textile, agriculture, daily chemicals and other industries.

Hydroxypropyl Methyl Cellulose products have different proportions of Methoxy and Hydroxypropyl, thus affecting the thermal gelation temperature of Hydroxypropyl Methyl Cellulose, and other property items.

In processed foods, Hydroxypropyl MethylCellulose has many excellent properties. According to the thermal gelation, film-forming, thickening and other properties it can be applied to different foods so as to enhance the taste of food. The formulation of bread contains 1% of Hydroxypropyl Methylcellulose, and gelation occurs in contact with hot oil. In this way, a protective layer can be formed at the edge of the frying food, greatly reducing the absorption of fat.

Application of SidleyCel™ Hydroxypropyl Methyl Cellulose in the Construction Industry: As the water-retaining agent and retarder of cement mortar, it enables the mortar to have pumping property. In plaster slurry, gypsum materials, putty powder or other building materials, it acts as a binder and helps to improve the spreadability and prolong the operating time.

Application of Hydroxypropyl Methyl Cellulose in PVC (Polrvinyl Chloride): In the production of PVC, it can act as a dispersing agent, the main additive in the preparation of PVC by suspension polymerization.

Applications

Description/Benefits

Medicine, Food Personal Industrial

As the product is non-ionic, and in the preparation process can be effectively purified by washing with hot water, it has a very low ash content. Hydroxypropyl Methylcellulose products can fully meet the standards for use of medicine, food, and personal care products.

Application Guide for PVC Industry

In the polymerization process of PVC suspension polymerization system, The use of Hydroxypropyl Methylcellulose as a dispersant can improve suspension dispersion properties, can also improve the particle morphology, and enhance the absorption performance on plasticizers.

Application Guide for Building Material Industry

Hydroxypropyl Methylcellulose has high water-holding capacity, can extend the working time of mortar, improve work efficiency and is good for the mortar to produce high mechanical strength during solidification.

Document  Library

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Effects of Hydroxypropyl Methyl Cellulose(HPMC) in Dry Mortar in Construction:Hydroxypropyl Methyl Cellulose has higher adhesion on mortar construction than methyl cellulose (MC). read more Solubility of Hydroxypropyl Methylcellulose (HPMC):Because Hydroxypropyl Methylcellulose (HPMC) does not dissolve in hot water, in the initial stage, Hydroxypropyl Methylcellulose can be evenly dispersed in hot water, and then it rapidly dissolves when cooled.read more  Application of Hydroxypropyl Methylcellulose in Food and Cosmetic Industries:Hydroxypropyl Methylcellulose can be added to fruit syrup and ice to make the taste better.read more Introduce Hydroxypropyl MethylCellulose (HPMC) :Besides, Hydroxypropyl Methylcellulose(HPMC) has thickening capacity, salt tolerance, low ash content, pH stability, water-retaining property, dimensional stability, excellent film-forming ability, extensive resistance to enzymes, dispersibility and cohesiveness. read more Properties of  HPMC (Hydroxypropyl MethylCellulose):Hydroxypropyl MethylCellulose is a non-ionic cellulose ether, in the appearance of white powder, odorless and tasteless. It is soluble in water, most polar organic solvents, and the appropriate proportion of ethanol/water, propanol /water and dichloroethane, but insoluble in diethyl ether, acetone, and anhydrous alcohol. read more What is Hydroxypropyl methyl cellulose ?Hydroxypropyl methyl cellulose (HPMC) is a polymer used for multiple applications in fields such as construction and ophthalmology. It is also known as hypromellose, which is the international, non-proprietary name (INN) for this substance. The name is not patented by any drug company, and can be used without fear of trademark or copyright infringement. HPMC is a solid substance at room temperature and is typically beige in color.One of the most important properties of hydroxypropyl methyl cellulose is that, in a water-based solution, it does not have a gelation property when heated. Instead of precipitating out as methylcellulose does, it causes the entire solution to congeal into a semi-flexible mass that can no longer flow. The more HPMC that is present, the lower the critical temperature needed to achieve this effect. read more What is hydroxypropyl methylcellulose?Hydroxypropyl methylcellulose is a semisynthetic polymer used for multiple applications including as an ophthalmic lubricant, as an excipient and controlled-delivery constituent in oral medicaments found in a range of commercial products. read more High-Molecular-Weight Hydroxypropylmethylcellulose Taken with or between Meals Is Hypocholesterolemic in Adult MenHydroxypropylmethylcellulose (HPMC) is a food gum that shares certain characteristics, such as high viscosity, with soluble fibers. In this trial, the safety and cholesterol-lowering efficacy of HPMC consumed with and between meals was evaluated in free-living male volunteers with mild-to-moderate hypercholesterolemia. Read more HYDROXYPROPYLMETHYL CELLULOSEPrepared at the 74th JECFA () and published in FAO JECFA Monographs 11 (), superseding the specifications prepared at the 63rd JECFA (), published in the Combined Compendium of Food Additive Specifications, FAO JECFA Monographs 1 (). A group ADI ”not specified” for modified celluloses (ethyl cellulose, ethyl hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropylmethyl cellulose, methyl cellulose, methyl ethyl cellulose, and sodium carboxymethyl cellulose) was established at the 35th JECFA ().more High-Viscosity Hydroxypropylmethylcellulose Blunts Postprandial Glucose and Insulin ResponsesHigh-viscosity hydroxypropylmethylcellulose (HV-HPMC) is a modified cellulose fiber that produces a viscous gel in the gastrointestinal tract. Clinical trials demonstrate that consumption of HV-HPMC significantly lowers cholesterol, but limited information has been available on the influence of HV-HPMC on postprandial insulin and glucose responses. The objective of this investigation was to assess the influence of HV-HPMC on postprandial glucose and insulin responses in overweight and obese men and women. more The rheological properties of isolated hydroxypropyl methylcellulose tissue engineering matricesCellulose ethers are water-soluble polymers derived from cellulose, the most abundant polymer in nature. They have been used for a long time in pharmaceutical and food industries, due to their ability to behave as emulsifiers, colloidal stabilizers, and flow controllers, but also owing to their non-toxic nature. Moreover, cellulose ethers exhibit appropriate biological properties which make them suitable for biomedical applications .Hydroxypropylmethylcellulose (HPMC) is a cellulose derivative polymer. HPMC is a methylcellulose modified with a small amount of propylene glycol ether groups attached to the anhydroglucose of the cellulose .moreHydroxypropyl methyl cellulose(CAS No. -65-3)

Hydroxypropyl methyl Cellulose (HPMC) , is non-ionic cellulose ether, and modified cellulose ether derivatives polymer that is off-white in color and considered safe for human consumption. It is odorless, tasteless, and in the shape of white powder. Hydroxypropyl Methyl Cellulose is made by mature high polymer cellulose as raw material and a series of chemical processing. It is used in various applications in construction, food, pharmaceutical, and personal care industries. It functions as a thickener, binder, film former, water retention agent, suspension aid, and a lubricant depending on the application.

HPMC, Hypromellose is a thickener for aqueous and non-aqueous systems, clear films with grease resistance, binders, lubricants, steric stabilizer and water retention aid. Dissolves in water, undergoes reversible gelation upon heating, non-ionic. According to their molecular weight or degree of substitution, it can form colloidal solution in water, it can not be soluble in solvent, the colloidal solution has the characteristics of high viscosity, adhesion, thickening, emulsifying, shaped, good water retention, protective colloid, film forming, acid resistance, salt tolerance, suspension and other characteristics, and the physiological harm. so it has been widely used in dry mix mortars, it is the most important additive for wall putty, tile adhesive, all kinds of gypsum and cement based dry mix mortars, it is also widely used in pharmaceutical as film forming, released control agent, it can be used for food thickening, emulsification, anti sedimentation.etc. Hydroxypropyl methyl cellulose (HPMC) can dissolve in both cold and hot water, add the appropriate water in a container, heated to 70 degrees Celsius, then keep stirring, adding hydroxypropyl methyl cellulose, it will form a slurry after cooling. This is the main solution of hydroxypropyl methyl cellulose, it is used in many different applications.

Application of HPMC

1.In Construction:

In dry mix mortars,  the dosage is very low (usually 0.2-0.7%) and it mix with cement/gypsum/sand etc. thoroughly, it can be soluble easily and no need to use hot water to disperse.As the water-retaining agent and retarder of cement mortar, it enables the mortar to have pumping property. In plaster slurry, gypsum materials, putty powder or other building materials, it acts as a binder and helps to improve the spreadability and prolong the operating time.Hydroxypropyl Methylcellulose has high water-holding capacity, can extend the working time of mortar, improve work efficiency and is good for the mortar to produce high mechanical strength during solidification.

2. In PVC industry:

In the production of PVC, it can act as a dispersing agent, the main additive in the preparation of PVC by suspension polymerization.In the polymerization process of PVC suspension polymerization system, The use of Hydroxypropyl Methylcellulose as a dispersant can improve suspension dispersion properties, can also improve the particle morphology, and enhance the absorption performance on plasticizers.

3. In Pharmaceutical, Food Personal care :

HPMC is non-ionic, and in the preparation process can be effectively purified by washing with hot water, it has a very low ash content. Hydroxypropyl Methylcellulose products can fully meet the standards for use of pharma, food, and personal care products.

Property of HPMC

Hydroxypropyl MethylCellulose is soluble in water, most polar organic solvents, and the appropriate proportion of ethanol/water, propanol /water and dichloroethane, but insoluble in diethyl ether, acetone, and anhydrous alcohol. In cold water, it will swell into a clear or slightly turbid colloidal solution.Its aqueous solution has surface activity, high transparency and stable properties. Hydroxypropyl MethylCellulose has thermal gelation properties, so after heating the aqueous solution will precipitate and form gels, and dissolve again after cooling. Products of different specifications have different gelling temperatures. Its solubility varies with the viscosity, and the lower the viscosity is, the greater the solubility will be. There are some differences in the properties of Hydroxypropyl MethylCellulose of different specifications. The dissolution of Hydroxypropyl MethylCellulose in water is not affected by the pH value.

1. Water retention Property: In wall putty/Skimcoat, the main roles of cellulose ether are water retention, adhesion, lubrication and so on. Hydroxypropyl MethylCellulose has high water-holding performance, surface opticity and improves uniformity. This helps to avoid crusting and off-powder phenomena, improve resistance to shrinkage, cracking and vertical flow, and to improve the work efficiency since the painting job is comfortable and saves effort.

2. Bio-Stability Property: Hydroxypropyl MethylCellulose has many features such as thickening power, salt discharge performance, pH stability, water retention, excellent film-forming properties, extensive resistance to enzymes, dispersion and adhesion.In water based paints and coatings, Hydroxypropyl MethylCellulose acts as film-forming agents, thickeners, emulsifiers and stabilizers, making the coating film with good wear resistance, leveling property, and adhesion, and improving the surface tension, pH stability, and compatibility with metal color materials. In the water-based paints, Hydroxypropyl MethylCellulose has excellent storage stability, maintains uniform viscosity, makes pigments uniformly dispersed, and basically won’t be affected by the pH value.

3. Disperse Property: In the production of synthetic resin, Hydroxypropyl MethylCellulose plays the role of protective colloidal agents and can effectively prevent polymeric particles from agglomerating. In the floating polymerization of vinyl chloride (VC), the disperse system has a direct impact on the product, PVC resin, and the quality of processing and products. It helps to improve the thermal stability of the resin and control the particle size distribution(that is, adjust the density of PVC). PVC resins made from high-quality cellulose ethers not only can ensure that the performance meets international standards, but also have apparent physical properties, fine particle characteristics and excellent melting rheological behavior.

4. Thickening Property: Hydroxypropyl MethylCellulose mainly functions as the thickening agent and can increase the the tensile strength and flexural strength. It also helps to improve surface coatings, enhance adhesion and improve the bonding strength of mortar. Furthermore, good permeability can improve the uniformity of the interface, enhance lubricity and fluidity of mortar, make coating easier and thus improve work efficiency.

5. Construct Property: In the bonding of tiles, tile adhesives can function as water-retaining agent and adhesives, and can greatly improve construction performance of adhesives, allow longer opening hours and greater cohesion, and prevent falling of tiles due to excessive water loss. Hydroxypropyl MethylCellulose has the properties of improving the workability, good water-retaining property, enhancing adhesion and high resistance to hanging. Hydroxypropyl MethylCellulose can improve the sticking and tiling efficiency, and also enhance bonding strength and shear strength.

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