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9 Steps To Picking The Right Industrial Centrifuge

Sep. 08, 2025

9 Steps To Picking The Right Industrial Centrifuge

Table Of Contents

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  • What are Industrial Centrifuges?
  • 1. Know the Fluid Contaminants.
  • 2. Identify the right type of centrifuge for your application.
  • 3. Understand the throughput capacity of industrial centrifuges.
  • 4. Select the right options for your centrifuge.
  • 5. Reputed-brand Centrifuge – New versus Remanufactured
  • Price of New versus Remanufactured Centrifuge
  • Typical delivery time of New and Remanufactured Centrifuges
  • Accessories available for New versus Remanufactured Centrifuges
  • Customization of New Centrifuges versus Remanufactured
  • 6. Remanufactured, Reputed-brand Centrifuge versus New, Generic Centrifuge
  • Quality
  • Design
  • Spare Parts
  • Serviceability
  • 7. Considerations in Choosing a Remanufactured Centrifuge
  • 8. Selecting a Remanufactured Centrifuge Supplier –OEM, Specialized Centrifuge Company, or Centrifuge Traders.
  • Types of Established and Experienced Centrifuge Supplier
  • Branded OEM’s
  • Super Specialized Centrifuge Companies
  • Generalized Centrifuge Companies
  • Application Experience of Centrifuge Supplier
  • Centrifuge Supplier’s Owned Inventory
  • Remanufacturing, Controls, Assembly & Testing – In-House or Subcontracted
  • Spare Parts and Spare Assemblies Availability
  • Sample Testing Service
  • Centrifuge Warranty
  • 9. Post Purchase Considerations
  • Factory Acceptance Test (FAT)
  • Technical Support
  • Factory and On-Site Startup Training
  • Summary
  • Questions, You (the buyer), should have answers for:
  • Questions to ask the potential centrifuge supplier:

Considering purchasing an industrial centrifuge but unsure where to begin? Even after thorough research, it's common to have lingering doubts and questions. Industrial centrifuges are significant capital investments that require meticulous consideration.

With our 40 years of expertise in the industrial centrifuge sector, we guide prospective buyers toward making informed decisions. We've distilled the centrifuge selection process into nine key steps to ensure you choose the appropriate industrial centrifuge.

Additionally, we've compiled a list of essential questions you should pose to your potential supplier.

by Sanjay Prabhu MSME
Engineering Manager, Dolphin Centrifuge

What are Industrial Centrifuges?

1. Know the Fluid Contaminants.

As they say, ‘Defining a problem is half the solution.’ Having a clear understanding of your separation needs and expected results is essential. To define your separation needs, you first need to understand the type of fluid and the type and amount of contaminants.

This necessary information is critical for us to understand your requirements and offer the right centrifuge.

In this initial stage, you have probably considered various separation technologies such as settling, filtration, hydro-cyclones, filter presses, screw presses, and other similar separation equipment. These technologies have a specific niche in the field, but few apply to a wide range of applications.

Having a good understanding of your specific requirements helps narrow down the available options.

2. Identify the right type of centrifuge for your application.

If you have already eliminated media-based separation (filters, presses, membranes, etc.) from your possible solutions, either a low or a high centrifugal force centrifuge may be appropriate.

If low g-force (< Gs of centrifugal force) centrifuges are not feasible due to particle size and fluid properties, higher speed and higher centrifugal force centrifuges may be worth considering.

Furthermore, many high g-force alternatives are appropriate for various applications. We have written a detailed article about the difference between decanter centrifuges and disc centrifuges. That article will help you narrow down the choice between decanter and high-speed disc centrifuges.

Another often ignored resource in the selection process is industry contacts. It is easy to reach out to colleagues or contacts within your industry to get recommendations on centrifuge types. In addition to referrals, you might even get to know the pitfalls and indirect advantages of various industrial centrifuges.

A centrifuge supplier can also be an excellent resource for identifying the right centrifuge for your application. Of course, you must know a supplier's natural bias and ensure that the selection satisfies the process requirements, standard vs. auxiliary equipment, financial considerations, vendor experience/expertise, and technical support/customer service.

We discuss the selection criteria for your centrifuge suppliers in a later section.

3. Understand the throughput capacity of industrial centrifuges.

As with all industrial equipment, centrifuges come in various sizes or capacities. Industrial centrifuge throughput capacities quite often confuse and mislead customers.

In other words, process capacity is the actual throughput a user can expect for their process fluid. Maximum capacity, also known as swallowing or hydraulic capacity, is the maximum flow rate the centrifuge can handle with water.

It is not uncommon for different vendors to quote vastly different capacities for the same centrifuge model. There are a few reasons for this anomaly.

First, the seller may not have a large centrifuge to handle your requirement. In that case, the ‘swallowing’ capacity (i.e., the hydraulic capacity) is misrepresented as the centrifuge’s process capacity.

Second, if the buyer is on a tight budget, the seller may try to sell a smaller capacity centrifuge by overstating the maximum capacity as potential process capacity.

Third, the seller does not possess the knowledge/experience to understand the buyer’s application. In this case, the seller may mention the OEM published capacity (max. Swallowing ability) as the processing capacity.

It is important to note that a specific centrifuge’s processing capacity depends on multiple factors, including:

  • Physical properties of the process fluid (Viscosity, Sp. Gravity)
  • Processing temperature
  • The difference in the specific gravity of the fluid phases (in the case of Liq/Liq Separation)
  • The percentage and particle size of solids in the fluid
  • The specific gravity of the separated solid particles

Based on the above, it is more important to understand how the centrifuge capacities are rated. It is equally important to ask the potential supplier to estimate the process flow rate for your fluid mix. If in doubt, the buyer may warrant additional research and search for a more informed supplier.

4. Select the right options for your centrifuge.

Auxillary equipment integral to centrifuge systems is also known as options. The main reason for adding options is to augment the working of the centrifuge to get maximum efficiency from the centrifuge.

Typical centrifuge options include pumps, sludge collection receptacles, in-line heaters, pre and post-filters, clean fluid collection and pumping systems, and other accessories.

It is important to note that what some suppliers consider standard (included) accessories, other suppliers may consider optional equipment.

For example, a control system, water harness (for sludge ejection controls), base platform (skid), gauges, instruments, and sensors, are standard accessories supplied with all centrifuges sold by Dolphin Centrifuge.

Some suppliers may consider these accessories as chargeable options. In other words, their scope of supply for a given price point may include a bare centrifuge with a motor. Therefore it is essential to make an ‘apples-to-apples comparison between different sellers’ scope of supply.

Depending on the application, there are specific options that we encourage our buyers to consider. For example, if a customer intends to process thick, used oil, we would strongly suggest an optional heater because lower viscosity (higher temperature) is key to efficient centrifugation of thick oils.

One of the most common complaints we hear from our customers is the lack of adequate heating capacity! It is much easier and cheaper to add a heating system during the centrifuge build process than to add one post-installation. Therefore we encourage our customers to err on the side of extra heat capacity.

Another example that illustrates the need for some optional equipment follows. Many centrifuges discharge the separated sludge through the bottom of the centrifuge frame. Customers may choose to install these centrifuges on elevated platforms to allow for sludge collection underneath.

However, adding the optional skid-integrated sludge collection and disposal system allows the skid to be flexible, i.e., mobile. It also eliminates the need for the customer to build a permanent platform.

In summary, we suggest evaluating and choosing the right options for your particular application from the start. The right choices can make the difference between average centrifuge performance and excellent centrifuge performance.

5. Reputed-brand Centrifuge – New versus Remanufactured

Every buyer would like a new centrifuge if it was not for budgetary or time constraints. For this discussion, we are discussing only centrifuges from established, brand-name manufacturers like Alfa Laval. We look at this consideration from 4 different aspects.

Price of New versus Remanufactured Centrifuge

A remanufactured centrifuge can save a buyer up to 50% compared to a new centrifuge. This cost savings is highly subjective and depends on the type, make, and centrifuge model.

Typical delivery time of New and Remanufactured Centrifuges

Lead time also plays a vital role in this decision of new versus remanufactured. Typical lead times for new centrifuge systems can be 8 to 18 months compared to those for remanufactured centrifuge systems, around 2 to 5 months.

Accessories available for New versus Remanufactured Centrifuges

Accessories (heaters, pumps, sludge systems, and filters) are important considerations for choosing between new and remanufactured centrifuges. New centrifuges from OEM generally come with proprietary accessories. This factor is important because the buyer depends on the OEM for these accessories’ parts and services.

For example, control systems from centrifuge OEMs are proprietary for their particular centrifuges. The control system program cannot be accessed or modified by the user. The OEMs cannot change the programs or control systems to suit buyers' needs.

Customization of New Centrifuges versus Remanufactured

The OEMs’ inability to customize is understandable, given many OEM systems, making customization impractical. This fact leads to other restrictions when dealing with new centrifuges from OEMs. The accessories (heaters, pumps, sludge systems) offered with new centrifuges are also proprietary. Parts and services of these additions are also highly dependent on the OEMs.

Non-OEM centrifuge suppliers with thorough knowledge and experience in centrifuges can address this issue. Dolphin Centrifuge is one of the few companies capable of bringing a high customization level to remanufactured centrifuges. We can use state-of-the-art technology to extract maximum performance from remanufactured OEM centrifuges.

In summary, a prospective buyer can see cost and lead-time benefits from choosing the remanufactured centrifuge option. Accessories and the ability to customize systems for unique applications also play a role in the final decision.

6. Remanufactured, Reputed-brand Centrifuge versus New, Generic Centrifuge

This section discusses another option available to centrifuge buyers, which is new, generic centrifuges. New, generic centrifuges refer to copies of brand-name centrifuges produced by third parties. The bulk of these centrifuges are manufactured in China and sold under various brands worldwide.

The primary reason for considering these generic centrifuges is their price point compared to new, reputed-brand centrifuges. However, the equation changes when comparing these generic centrifuges to remanufactured reputed-brand (like Alfa Laval) centrifuges.

In other words, a customer can source an Alfa Laval centrifuge, which is remanufactured in the US at a similar price point to a new, generic centrifuge. At the same price level, the advantages of the remanufactured, branded centrifuge are apparent.

Some of these advantages are listed below.

Quality

Reputed brand centrifuges such as Alfa Laval have more than 100 years of manufacturing experience. They are well known for their material quality and robust design. These branded centrifuges are commonly known to last over 50 years. Generic centrifuge manufacturers cannot easily make such claims.

Design

R&D is a significant part of all branded centrifuge manufacturing operations. R&D allows manufacturers like Alfa Laval to incorporate the latest learnings and technologies into their evolving centrifuges.

Generic centrifuge manufacturers do not typically have any R&D but rely on their low price point as the primary selling feature.

Spare Parts

Branded centrifuges have been around long enough to create their spare parts ecosystem. Consequently, genuine and aftermarket parts for branded centrifuges are readily available worldwide.

Generic manufacturers use parts specific to only their centrifuges. Getting spare parts for these centrifuges can not be assured.

Serviceability

With thousands of units in operation worldwide, branded centrifuges are familiar to centrifuge technicians worldwide. Therefore servicing of branded centrifuges is readily available in most locations.

Generic centrifuge copies are not as widely prevalent as their branded counterparts. Experienced service technicians can be hard or impossible to find outside of the manufacturer’s technicians.

7. Considerations in Choosing a Remanufactured Centrifuge

Remanufactured is a loosely used term, the scope of which is dependent on the remanufacturer. A remanufactured centrifuge from a used equipment dealer could mean a paint coat on a barely functional centrifuge compared to a complete, ‘rebuilt from scratch centrifuge’ from a reputed centrifuge company.

Some of the other factors to consider in a remanufactured centrifuge are the centrifuge’s prior use and present location. Following is an explanation of each of these factors.

Prior use of the centrifuge refers to the previous application of the centrifuge in its earlier life. For example, a centrifuge from a highly abrasive application like sand or drilling mud needs careful inspection before consideration. It is not easy to revive centrifuge bowl components with excessive wear. A worn-out bowl limits the useful life of the centrifuge.

The present location of the centrifuge under consideration is essential if the centrifuge is in a distant geographical area from the seller. In such cases, it is difficult for the seller to perform a thorough inspection of the centrifuge before buying.

Ideally, the seller should have the centrifuge on offer physically inspected and available for the prospective buyer’s inspection before purchase.

8. Selecting a Remanufactured Centrifuge Supplier –
OEM, Specialized Centrifuge Company, or Centrifuge Traders.

OEMs, specialized centrifuge companies, and centrifuge traders all sell ‘remanufactured’ centrifuges. Selecting the right supplier is one of the most critical choices facing a potential buyer – whom should you buy from?

We will break down this selection step into factors worth considering while choosing the right supplier for your industrial centrifuge.

Types of Established and Experienced Centrifuge Suppliers

Branded OEM’s

A branded OEM is an established company. For example, Alfa Laval, the gold standard in centrifuges, has been around for over 100 years. They should be the first choice for any buyer looking for a remanufactured centrifuge. However, as noted in Section 5, this is often not feasible due to cost concerns.

Super Specialized Centrifuge Companies

Finally, super-specialized centrifuge companies specialize in certain types of centrifuges and cater only to that specific market. Dolphin Centrifuge is one such company that specializes in decanter and disc centrifuges. Within that sub-category, we specialize in Alfa Laval branded centrifuges.

Generalized Centrifuge Companies

Generalized centrifuge companies sell all different types and brands of remanufactured centrifuges. Some of these companies have been in business for over 25 years. There are a few different types of companies within this category.

Centrifuge traders buy and sell all varieties of industrial centrifuges, from basket centrifuges to pusher centrifuges to decanter and disc centrifuges. Then, centrifuge repair companies specialize in repairing and ultimately selling used centrifuges of different types.

Application Experience of Centrifuge Supplier

The application experience is a critical differentiating factor worth considering. As discussed in the previous point, generalized centrifuge traders cater to all markets and applications. They offer a wide selection; however, they may lack in-depth application experience. These traders tend to be more generalized and could be a good source for buyers with in-house centrifuge expertise.

On the other hand, OEMs have various divisions within their company, each with in-depth application experience catering to specific sectors.

Centrifuge suppliers specializing in specific types of centrifuges tend to have in-depth application experience. This fact is especially true for specialized centrifuge suppliers. They are established and have been in the business long enough to have experience with practically all applications of their specific machines.

Centrifuge Supplier’s Owned Inventory

Centrifuge supplier’s owned inventory refers to the stock of centrifuges owned by the potential supplier. This owned inventory is an essential consideration for potential buyers for the reasons explained below.

The main component of the centrifuge is the rotating bowl, which is the heart of the centrifuge. While frame and transmission parts can be repaired or replaced, the centrifuge bowl is not recoverable from excessive wear.

Some established centrifuge suppliers buy and stock gently used centrifuges whenever and wherever they are available. This inventory of pre-selected centrifuges offers the supplier the advantage of providing centrifuges with minimal wear bowls.

OEMs have a similar advantage of having a stock of gently used centrifuges, which they receive as trade-ins.

Suppliers who don’t have their stock of pre-selected centrifuges often seek used centrifuges once they have a buyer's purchase commitment. At this point, it is not always possible to find centrifuges having bowls without significant wear. There is also the likelihood of procuring the least cost centrifuge at this point in the transaction.

In summary, it is worth inquiring about the ownership of the proposed centrifuge for the reasons above.

Remanufacturing, Controls, Assembly & Testing – In-House or Subcontracted

A remanufactured centrifuge system involves certain sub-activities that are critical to the long-term trouble-free operation of the centrifuge.

These activities cover the following main areas:

  • Remanufacture of the centrifuge machine
  • Design and assembly of the control system
  • Fabrication of the skid components
  • Assembly, wiring, and testing of the complete system

OEMs have specific remanufactured centrifuge divisions which integrate all of the above under one roof. The result is a fully integrated centrifuge system with an assured durable operation.

Few specialized centrifuge suppliers can perform all of these activities in-house. Dolphin Centrifuge is one such dedicated centrifuge supplier.

Generalized centrifuge traders cannot have all these facilities in-house because of their broad scope of supply.  Therefore, it is not uncommon to see the centrifuge seller, the remanufacturer, the controls builder, and the system integrator being separate, independent companies or individuals. The expertise and knowledge are lost if there isn’t a single entity ownership or diverged focus.

The advantage of this process is the potential time savings from leveraged independent resources. However, there is no single point of contact or knowledgeable source for support in post-sales issues or technical support.

There is no corporate memory to implement the ” lessons learned” into future centrifuge systems under these circumstances. These learnings relate to inter-component issues, such as specific control features modified based on certain centrifuge features particular to the application.

Finally, the system build location becomes critical if imported subsystems are involved. The system's origin is crucial due to the difference between North American and European/Asian engineering standards.

For example, control panel components, motors, fasteners, and other components adhere to different standards depending on the location. These differences can be a significant issue when users cannot find a simple fastener or electrical component anywhere in the local market.

Spare Parts and Spare Assemblies Availability

As mentioned in section 6 above, spare parts availability is one of the advantages of choosing a branded centrifuge OEM. However, specialized centrifuge suppliers can also afford to carry a large spare parts inventory. The availability of spare parts is due to their narrow focus on specific centrifuges.

On the other hand, generalized centrifuge traders cannot carry all the spare parts for the different brands and types of centrifuges. Of course, there are other sources of generic spare parts for branded centrifuges. But then the buyer has to find and source spare parts independently.

Spare parts are not always ‘spare’! Often the centrifuge operator is looking for parts when there is a breakdown. At this point is a time-sensitive situation, and a centrifuge supplier who also carries parts for the centrifuges they sell is beneficial.

Spare assemblies refer primarily to bowl assemblies. It is easier to find used bowl assemblies for branded centrifuges, which are prevalent in the market.

A specialized centrifuge supplier with a stock of centrifuges is your first choice for spare centrifuge bowl assemblies. They can offer sound, reusable bowl assemblies from their pre-selected stock. This availability also applies to frame assemblies and other large, expensive parts.

Sample Testing Service

OEMs offer a sample testing service wherein they process a small sample of the potential customers’ fluid through a pilot-scale, high-speed centrifuge to evaluate centrifuges’ applicability.

Few other centrifuge suppliers offer this service. However, it is recommended since it can provide additional assurance of centrifuge applicability to the customer.

Some specialized centrifuge suppliers can process a customer sample and provide a detailed test report. Based on their experience, they can also make centrifuge recommendations depending on the rest results.

The ability to test your sample is a question worth asking all your potential centrifuge suppliers.

Centrifuge Warranty

A warranty is only as good as the company behind the warranty. One important consideration with a centrifuge warranty is that it is a mechanical warranty.

Link to Grace

Given that a centrifuge is a mechanical separation device, it is impossible to provide a process warranty. This inability to provide a process warranty is because different fluid properties, operating conditions, and machine settings will produce differing results. Therefore there is no way to predict and guarantee process results.

9. Post Purchase Considerations

This final step will discuss the importance of some post-purchase factors that the buyer should consider before making the final purchase decision. We have divided this section into three important after-sales factors.

Factory Acceptance Test (FAT)

The factory acceptance test is an opportunity for the buyer to visit the supplier’s factory and witness the final testing of the centrifuge they purchased. FAT is an excellent opportunity for the buyer to inspect and see their centrifuge system operating.

FAT is routinely offered by OEMs, especially when their customers have the FAT as part of the buying process.

Specialized centrifuge companies, such as Dolphin Centrifuge, offer FAT and see it as an opportunity to familiarize their customers with the centrifuge. It is also a chance for the customer’s operators to get some hands-on experience with the equipment under the supplier’s guidance.

Some generalized centrifuge traders may offer FAT if specifically requested. It will depend upon the system integrator's actual testing location and availability, who may not be the seller.

Technical Support

Centrifuges are durable machines, but they are not filters! In other words, they are machines, and machinery needs to be maintained to ensure reliable operation. Also, centrifuges are not familiar machines.

As a result, after-sales technical support is all the more critical for centrifuges. In-depth centrifuge knowledge and experience are required to offer technical support.

Specialized centrifuge suppliers are well-equipped to provide reliable technical support and maintenance. Their ability to offer tech support is due to their narrow focus on the centrifuges they specialize in. Their dedicated focus gives them a deep understanding of centrifuge products and helps in unique situations.

It is worth mentioning here that Dolphin Centrifuge offers lifetime technical support to all our customers.

Factory and On-Site Startup Training

As mentioned above, under the FAT section, customers can send their operators to the supplier during the FAT to get initial training. OEMs and certain specialized centrifuge manufacturers offer FAT. One can consider FAT as factory training.

Though the OEMs typically charge for FAT, specialized centrifuge suppliers (such as Dolphin Centrifuge) include this service without an additional charge.

Both OEMs and specialized centrifuge remanufacturers offer on-site training. This training helps the customer fine-tune the centrifuge on their actual process fluid on continuous flow. The customer’s operators can understand the centrifuge, control system, and servicing procedures.

Most generalized centrifuge traders offer on-site training as well. But again, depending on the centrifuge trader, a generic centrifuge technician may not have the in-depth knowledge to answer all questions. This lack of knowledge is especially the case if the technician is unfamiliar with the centrifuge and the controls are from a 3rd party.

Summary

Selecting the correct centrifuge for your needs is a significant decision. It would be best to consider many factors to choose a centrifuge that works efficiently; it can be easily serviced and at an appropriate price point.

We can summarize the steps mentioned earlier in the form of questions that a prospective centrifuge buyer should ask as they go about selecting a centrifuge and vendor. The answers to these questions will give the customer enough information to make an informed buying decision.

Questions, You (the buyer), should have answers for:

What are the properties of your process fluid?

  • Viscosity
  • Specific Gravity of All Fluids
  • Operating Temperature of Fluid
  • Solid Particle Size (if solids present)

Is this Liquid/ Liquid or Liquid/ Solid or Liquid/ Liquid/ Solid separation?

What is your capacity requirement? How many gallons per minute?

What is the % of each phase in your process fluid?

Which phase(s) are you trying to recover? (i.e., Valuable Phase)

Do you need equipment for hazardous areas or Explosion Proof classified?

Questions to ask the potential centrifuge supplier:

What data do you need from us to recommend a centrifuge for our application?

What are the rated capacity and expected process capacity on the process fluid of the centrifuge you are offering?

How should we pre-treat our process fluid to get the maximum out of the centrifuge?

What accessories do you include with the centrifuge?

Do you recommend we include any additional options? If so, why?

Can you offer the same or a similar centrifuge as a new one? If so, what is the price and delivery time difference?

Who is the original manufacturer of the centrifuge offered? Where was it manufactured, and is the manufacturer still operational?

Are spare parts readily available for this centrifuge? If so, can you refer us to a local (US-based) source?

What was this centrifuge used for in its prior use?

Where is this centrifuge presently located? Is it available for inspection before we decide to buy it?

How long have you been in business?

Can you share a portfolio of centrifuges you have supplied?

Have you previously supplied a centrifuge for this application? If so, can you share the details?

Do you currently own the centrifuge you are offering?

Who will remanufacture the centrifuge?

Where will it be remanufactured?

Who will design and build the control system? Where will it be made?

Where will the complete system be integrated, wired, and tested? Will you be present?

Do you carry spare parts for this centrifuge? What about additional bowl assemblies?

Can you test a sample of our process fluid and give us your recommendation?

What kind of warranty do you offer? Can we see your warranty statement?

Can we witness the testing of the centrifuge?

If we need technical assistance with the centrifuge – whom do we call?

If we need technical assistance with the control system – whom do we call?

Can you train our operators at your facility on our centrifuge?

If we need on-site startup assistance, who will provide that support?

We hope this article will help prospective centrifuge buyers to make an informed decision on their centrifuge purchase.

by Sanjay Prabhu MSME
Engineering Manager, Dolphin Centrifuge

Guide to Purchasing a Professional-Grade Pre-Owned Centrifuge

Professional-grade centrifuges are essential workhorses in laboratories that demand high-throughput separations and reproducible performance. These high-capacity, floor-standing systems are commonly found in biopharmaceutical production, clinical diagnostic labs, and academic research centers. Unlike benchtop units, floor centrifuges can handle larger volumes, achieve higher g-forces, and run continuously for extended workflows. These instruments cost from $40,000 to $100,000 or more when purchased new. However, buying a professionally refurbished model often reduces that investment by 40 to 70 percent while offering reliable performance.

Researchers, lab managers, and procurement teams can confidently choose a centrifuge from trusted manufacturers like Beckman Coulter and Thermo Scientific by focusing on the right features and performance benchmarks, and then selecting a quality pre-owned equipment provider.

Understanding Floor Centrifuges

Professional-grade floor centrifuges are essential in laboratories with routine high-throughput, precision-based sample processing. Unlike benchtop units, floor models offer distinct advantages: they can handle multiple liters per run, reach significantly higher speeds and g-force ranges, and maintain reliable performance during continuous workflows. These attributes make them indispensable for demanding applications such as viral vector preparation, large-scale cell harvesting, blood component separation, sample pelleting, and density gradient separations.

In biomanufacturing, producing and purifying viral vectors for gene therapies and vaccines requires rigorous separation protocols. Benchtop centrifuges often lack the speed and capacity to meet clinical or GMP standards. Floor centrifuges, by contrast, deliver the high speeds, often exceeding 60,000 x g, required for gradient ultracentrifugation. In an empirical study by Mekkaoui and colleagues (), high-speed floor centrifugation was used to purify γ-retroviral vectors, achieving concentrated titers suitable for clinical-grade applications with minimal infectivity loss. These findings confirm that floor centrifuges are scalable and effective in maintaining biologics' functional integrity during processing.

Similarly, floor centrifuges outperform benchtop alternatives in cell harvesting workflows, particularly with high-density mammalian cultures like CHO or HEK293 cells, enabling continuous solids discharging and significantly larger batch processing. A study published in Continuous Solids Discharging centrifugation to Solve Clarifying High-Cell-Density Mammalian Cell Cultures (n.d.) showed that using floor centrifuges for clarifying high-density cell cultures resulted in a 40 percent increase in viable cell recovery and a marked reduction in processing time. This efficiency is particularly valuable in upstream bioprocessing pipelines, where speed and consistency directly impact overall yield.

The advantages of floor centrifuges extend into clinical laboratories, where separating blood components is a routine but critical task. Benchtop units are limited in throughput and typically require multiple batch runs. Floor models such as the Thermo Scientific Cryofuge 16 can handle up to 16 large-volume blood bags in a single cycle, allowing simultaneous separation of red blood cells, plasma, and platelets. A clinical evaluation by Cid and colleagues () demonstrated that floor centrifuges maintained consistent product yields and reduced operator time, reinforcing their role as a reliable solution in transfusion services and hospital labs.

In downstream applications such as sample pelleting, floor centrifuges again prove their superiority. Where benchtop models may require repetitive cycles to pellet cells, floor centrifuges with superspeed rotors can achieve the same results in a single run with higher efficiency. Research documented enhanced yield and pellet integrity during high-volume E. coli and yeast centrifugation using rotors configured for 6 x 1,000 mL bottles (RC, ). These improvements contribute to more reliable protein purification and nucleic acid extraction protocols.

Finally, the floor ultracentrifuges' enhanced control and stability become essential in the density gradient separations required for isolating viruses or organelles. While benchtop centrifuges often fail to sustain the necessary RCF and temperature precision, floor units provide consistent conditions for extended runs. A study in Separations demonstrated successful isolation of rat liver peroxisomes using iodixanol gradients, yielding organelle fractions with over 90% purity, performance only achievable with advanced floor centrifugation systems (Baz et al., ).

By delivering superior performance across a spectrum of scientific workflows, floor centrifuges remain a cornerstone of modern laboratory infrastructure. They offer the capacity, consistency, and precision that benchtop models simply cannot match.

Key Features to Evaluate in Pre-Owned Floor Centrifuges

When purchasing a pre-owned floor centrifuge, a thorough evaluation of its components and operating specifications is essential to ensure reliable performance and long-term safety. Start by assessing rotor compatibility. Determine whether your applications call for swinging-bucket rotors, which maintain tubes in a horizontal orientation and are ideal for density gradients or blood component separation, or fixed-angle rotors, which hold tubes at an angle and are better suited for rapid pelleting of cells, bacteria, or precipitates. Check the specific rotor model, maximum RPM, and capacity, as these will directly influence throughput and suitability for your protocols. Critically inspect rotors for signs of metal fatigue, such as pitting, corrosion, or hairline cracks, so it is good to  request photos of the rotor so you can confirm the condition.

Next, evaluate the refrigeration system, especially if you work with temperature-sensitive samples like enzymes, blood products, or live cells. Confirm that the unit can consistently reach and maintain its cooling range, which typically extends from ambient to 4°C or lower. Inquire about the age and health of the compressor, whether it cycles properly. Also, ask if the condenser coils or internal fans have been cleaned or replaced during refurbishment. Service logs or testing results if available can help verify that the system has held temperature under load.

The drive system and motor assembly form the mechanical backbone of a floor centrifuge, and their condition should be carefully tested. Most modern units use brushless induction motors, which are known for longevity and low maintenance. These motors should operate smoothly across the entire speed range, without unusual noise or vibration, which can signal wear in the bearings or imbalanced internal components. Confirm that the rotor coupling mechanism engages and disengages properly and that the unit accelerates and brakes as expected. Ask for a video of the centrifuge running with the sound turned on to confirm there are no unusual noises indicating possible issues. This can be provided right 

Modern floor centrifuges often include digital control panels, offering features such as touchscreen displays, programmable run profiles, rotor recognition, and networking capabilities. Ensure that all buttons, screens, and sensor outputs are fully functional. If the model includes data export via USB, Ethernet, or LIMS integration, verify that all necessary ports and software functions are included and operational. This is especially useful in regulated environments, where digital speed, time, and temperature tracking can support compliance with GMP, GLP, or ISO standards.

Centrifuge safety systems must also be operational and verified. These include imbalance detection, which halts operation if sample loads are uneven; overspeed protection, which prevents the rotor from exceeding safe RPM; and lid interlocks, which ensure the lid stays locked during operation and only opens once the rotor comes to a full stop. Ask sellers to test these features during inspection or request video demonstrations if buying remotely. Ask for a decontamination certificate to be provided if the centrifuge has been used with biohazardous materials. This certificate is often required for safety audits or when moving equipment across facilities or borders.

Finally, consider power requirements and physical footprint before committing to a purchase. Most floor centrifuges operate on 208–240V power, with some requiring single-phase and others three-phase connections. Ensure your lab’s infrastructure supports the unit, including the correct outlet type and circuit amperage. If they are a reputable dealer and the system is adjustable, ask to have the voltage adjusted if possible. Floor models are heavy and bulky, often weighing often weighing 250–400 kg (550–880 lbs), so you’ll also need to verify that your lab has enough space, including ventilation clearance and lid lift height. Confirm whether the centrifuge’s heat output, noise levels, or airflow design comply with environmental control protocols for labs with cleanrooms or containment zones.

Before making a final decision, align the centrifuge’s specifications, rotor type, speed, capacity, software, and certification potential with your lab’s specific needs and workflow. Buying a centrifuge that matches your facility’s infrastructure and regulatory environment will reduce setup friction and ensure the instrument becomes a seamless part of your operations. 

Beckman Coulter Floor Centrifuges

Beckman Coulter is a trusted name in lab instrumentation, and their centrifuges are known for longevity, safety, and rotor innovation. Common models include the Avanti J series (J20, J26 XP, JXN), which balances speed and capacity, and the J6-MI, which is optimized for high-volume, low-speed applications. The Optima ultracentrifuge series (e.g., XE, XPN) is widely used for high-speed molecular separations.

Beckman centrifuges feature ARIES self-balancing rotors and robust drive systems. Their rotors are typically backward-compatible across models, allowing labs to reuse existing accessories. Units like the Optima XPN include advanced software, user authentication, and audit logs for regulated environments. Integrating these features means Beckman models are frequently deployed in cGMP-compliant manufacturing settings, where data integrity and traceability are paramount.

Thermo Scientific Floor Centrifuges

Thermo Scientific’s Sorvall line includes several standout floor models. The Lynx and offer high speeds with intuitive touchscreens and noise-dampening drive systems. The Sorvall BIOS 16 is designed for bioprocessing, with a 16-liter capacity and exceptional rotor flexibility. Thermo also offers ultracentrifuge models like the Sorvall WX+, which reach speeds up to 100,000 RPM.

Thermo units are known for ergonomic design and safety features. The Auto-Lock rotor system simplifies rotor changes without tools. Auto-ID ensures safe operation by recognizing the rotor and adjusting speed limits automatically. Carbon fiber Fiberlite rotors offer a long lifespan and reduced weight, improving usability and decreasing fatigue-related risks.

Verify that rotor accessories such as buckets, spacers, and adapters are included when purchasing used Thermo models. For older models, check the condition of drives, refrigerants, and key electronic components. Contact Thermo for a history of firmware revisions or service bulletins that may affect performance or compatibility.

Questions to Ask the Seller

Before purchasing, ask whether the manufacturer still supports the model and whether spare parts are readily available. Confirm whether the seller offers a warranty, what it covers, and how long it lasts.

Ensure the centrifuge has been decontaminated. Ask for maintenance records, including any service performed, component replacements, or calibration history. Confirm that all accessories and manuals are included and ask whether installation or training support is offered. Finally, ask whether there are any known issues or recurring faults with the unit.

For high-value purchases, request a test report showing the centrifuge reached its max rated speed and temperature. Inquire about the conditions under which it was stored or used previously (e.g., academic lab vs. industrial plant). Some sellers may also offer a video demonstration or virtual walkthrough.

Where to Purchase Professional-Grade Pre-Owned Centrifuges

Purchasing from a reputable lab equipment reseller helps ensure the centrifuge has been professionally tested, serviced, and supported after sale. Trusted resellers inspect each unit thoroughly, often including warranties, calibration verification, and shipping coordination.

Boston Industries Inc., based in Walpole, Massachusetts, is a leading resource for high-quality refurbished centrifuges from manufacturers like Beckman Coulter and Thermo Scientific. Their team cleans, services, and tests each centrifuge before it leaves the facility. Every unit is verified for performance, including temperature control, drive function, advanced friction reduction systems and safety features.

Boston Industries products include warranty coverage backed by professional technicians, with extended coverage available on many instruments, along with detailed documentation, photos, and testing records upon request. Customers can also visit to preview and demo equipment in person. The company provides professional crating and worldwide shipping, ensuring delivery is straightforward and secure.

Boston Industries focuses on delivering value to labs that need reliable equipment while working within a budget. Their inventory, service quality, and attention to detail make them a dependable choice for anyone looking to invest in a professional-grade pre-owned centrifuge.

Making the Investment Count

After installation, ensure the centrifuge integrates smoothly into your lab’s workflows. Train users on proper setup, balancing, and maintenance. Post SOPs and quick-start guides to promote consistency, especially in shared lab environments or facilities with rotating staff and varying experience levels.

Plan for scalability by choosing a model that supports additional rotors, adapters, or software features. This flexibility allows your centrifuge to grow with your lab’s evolving research or production needs. Maintain detailed records of service, calibration, and performance checks. For GMP, GLP, or ISO-certified labs, document installation qualification (IQ), operational qualification (OQ), and calibration results. Use third-party validation services if internal resources are limited.

Keep an active relationship with your vendor for support. A reliable centrifuge should function as a long-term platform—adaptable, compliant, and aligned with your lab’s current priorities and future goals.

Conclusion

Selecting a professional-grade pre-owned centrifuge is a cost-effective way to access high-performance lab equipment without compromising reliability or compliance. Floor centrifuges from trusted manufacturers like Beckman Coulter and Thermo Scientific offer the capacity, speed, and rotor flexibility required for demanding applications in biomanufacturing, clinical diagnostics, and research. When purchasing refurbished equipment, it’s essential to evaluate rotor compatibility, system condition, and documentation to ensure safety and performance.

Partnering with a reseller like Boston Industries Inc. assures that the centrifuge has been tested, serviced, and backed by warranty. For labs seeking to optimize their workflows, stay compliant, and scale over time, consulting with a knowledgeable expert is the best way to ensure the instrument fits current and future needs.

References

Baz L, Al-thepyani M, Salha Algarni, & Gashlan H () Isolation of peroxisomes from frozen liver of rat by differential and iodixanol gradient centrifugation Separations, 10(5), 306–306.

Cid J, Comasòlivas N, Pérez‐Aliaga A, Illingworth N, & Cardoso M () Comparison of automated versus semi‐automated whole blood processing systems: A systematic review Vox Sanguinis

Continuous solids discharging centrifugation to solve clarifying high-cell-density mammalian cell cultures (n.d.)

Mekkaoui L, Tejerizo J G, Abreu S, Lydie Rubat, Aleksandra Nikoniuk, Macmorland W, Horlock C, Matsumoto S, Williams S, Smith K, Price J, Srivastava S, Hussain R, Banani M A, Day W, Stevenson E, Madigan M, Chen J, Ravin Khinder, & Miah S () Efficient clinical-grade γ-retroviral vector purification by high-speed centrifugation for CAR T cell manufacturing Molecular Therapy — Methods & Clinical Development, 28, 116–128.

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